Tianjin Finder Chemical

Cat.	Compound	CAS	MW	Spec	Purity	Per unit	Order
TR5	Tirzepatide C225H348N48O68	2023788-19-2	4813.45	5mg*10vials	≥99.0%	$40	ORDER →
SM2	Semaglutide C187H291N45O59	910463-68-2	4113.58	2mg*10vials	≥99.0%	$30	ORDER →
TR30P	Tirzepatide 30mg Pen Kit C225H348N48O68	2023788-19-2	4813.45	30mg*10 pens (click-dose)	≥99.0%	$250	ORDER →
RT5	Retatrutide C221H343N47O67	2381089-83-2	4731.0	5mg*10vials	≥99.0%	$65	ORDER →
RT30P	Retatrutide 30mg Pen Kit C221H343N47O67	2381089-83-2	4731.0	30mg*10 pens (click-dose)	≥99.0%	$335	ORDER →
BT5	TB-500 (TB4) C43H69N12O12P	77591-33-4	889.01	5mg*10vials	≥99.0%	$65	ORDER →
B10F	TB-500 FRAG C43H69N12O12P	77591-33-4	889.01	10mg*10vials	≥99.0%	$85	ORDER →
BC5	BPC-157 C62H98N16O22	137525-51-0	1419.55	5mg*10vials	≥99.0%	$35	ORDER →
2AD	AOD9604 C78H125N23O23S2	221231-10-3	1817.05	2mg*10vials	≥99.0%	$45	ORDER →
BB10	BPC157 5mg + TB500 5mg Blend C62H98N16O22	137525-51-0	1419.55	10mg*10vials	≥99.0%	$85	ORDER →
BB20	BPC157 10mg + TB500 10mg Blend C62H98N16O22	137525-51-0	1419.55	20mg*10vials	≥99.0%	$150	ORDER →
BBG50	GLOW GHK-CU 35mg+TB500 10mg+BPC157 5mg C62H98N16O22	137525-51-0	1419.55	50mg*10vials	≥99.0%	$150	ORDER →

Standards aligned ICH Q2(R1) ICH Q3D ICH Q3C ICH Q7 ICH Q1A(R2) USP <71> USP <85> USP <61> USP <62> USP <788> USP <1226> EP 2.6.14 EP 2.9.20 JP 4.01 ISO 9001:2015 ISO/IEC 17025

Analytical record · Lot B-2026-0428-001

Reference standard — full analytical profile

Every batch is released against a written specification with identity (LC-MS), assay (RP-HPLC), endotoxin (LAL), water (Karl-Fischer), residual solvents (GC-headspace) and microbial limits — recorded on a per-lot Certificate of Analysis.

RP-HPLC trace · purity

Tirzepatide

Rt 12.84 min
99.74%

ESI-Q-TOF MS · identity

[M+H]⁺ confirmed

m/z 100 – 6000
±0.3 Da

Purity (HPLC)

99.74%

UV-DAD 220 nm · A%

Identity (MS)

[M+H]⁺ ✓

±0.3 Da of theoretical

Endotoxin

< 0.05 EU/mg

LAL kinetic · USP <85>

Water (KF)

2.3% w/w

Coulometric titration

Certificate of Analysis

Tirzepatide · Lot B-2026-0428-001

Mfg 2026-04-28
Exp 2029-04-28

Compound	Tirzepatide
CAS number	2023788-19-2
Molecular formula	C225H348N48O68
Molecular weight	4813.45 g/mol
Appearance	White to off-white lyophilised cake
Solubility	Freely soluble in water (≥ 5 mg/mL); soluble in 0.1 M acetic acid
Identity (ESI-Q-TOF)	[M+H]⁺ ±0.3 Da of theoretical · matches reference spectrum
Assay (RP-HPLC, A%)	99.74% (Spec ≥ 98.0%)
Net peptide content	88.4% w/w (AAA)
Endotoxin (LAL kinetic)	< 0.05 EU/mg · USP <85> (Spec < 5.0 EU/mg)
Microbial — TAMC	< 10 CFU/g · USP <61> (Spec < 100)
Microbial — TYMC	< 10 CFU/g · USP <61> (Spec < 10)
Specified microorganisms	Absent · USP <62> (S. aureus / E. coli / P. aeruginosa)
Water content (KF)	2.3% w/w (Spec ≤ 5.0%)
Acetate counter-ion	7.8% w/w · ion chromatography
TFA residual	< 1.0% · ¹⁹F-NMR
Heavy metals (total)	< 10 ppm · ICH Q3D · ICP-MS
Form	Lyophilised, sterile-filtered (0.22 μm), N₂-purged amber glass vial

Backbone topology · structural reference

Tirzepatide · primary structure

Fmoc-SPPS · TFA cleavage · RP-HPLC purified

— Reference standard programme · synthesis → QC → release —

Endotoxin · microbial limits · elemental impurities

USP <85> · <61> · <62> · ICH Q3D

Bacterial endotoxins

< 0.05 EU/mg

LAL kinetic chromogenic · USP <85>

Total aerobic count

< 10 CFU/g

USP <61> · TAMC

Total yeast / mould

< 10 CFU/g

USP <61> · TYMC

Specified microorganisms

absent

USP <62> · S. aureus / E. coli / P. aeruginosa

Heavy metals (total)

< 10 ppm

ICH Q3D · ICP-MS · Pb/Cd/As/Hg

Sterility · USP <71>

no growth

14-day · FTM + SCDM · membrane filtration

Acetate content

7.8% w/w

Counter-ion · ion chromatography

TFA residual

< 1.0%

Trifluoroacetate · ¹⁹F-NMR

Residual solvents — ICH Q3C(R8)

GC headspace · FID

Class	Solvent	PDE / limit	Result	Status
Class 1	Benzene	2 ppm	not detected	● pass
Class 1	Carbon tetrachloride	4 ppm	not detected	● pass
Class 2	Acetonitrile	410 ppm	38 ppm	● pass
Class 2	Dichloromethane	600 ppm	21 ppm	● pass
Class 2	N,N-DMF	880 ppm	112 ppm	● pass
Class 3	Ethanol	5000 ppm	86 ppm	● pass
Class 3	Ethyl acetate	5000 ppm	42 ppm	● pass

Container · closure system

2 mL Type I amber borosilicate glass vial · 13 mm bromobutyl-rubber stopper (B2-40, FluroTec® coated) · aluminium flip-off seal · headspace purged with dry N₂. Tested per USP <1660> · <381> · <671> for moisture vapour transmission.

Particulate matter · USP <788>

Method 1 · light obscuration. ≥ 10 μm: 18 / mL (limit ≤ 6000); ≥ 25 μm: 1 / mL (limit ≤ 600). Reconstituted 1 mg/mL in water-for-injection. EP 2.9.19 cross-validated. Pass.

Bioactivity · receptor binding

In-vitro binding assay vs. cognate reference standard. EC₅₀ relative potency 96 – 104% (n=3). cAMP accumulation HEK-293 stable line · LANCE® TR-FRET · 4-parameter logistic fit. Within ±10% spec.

Real-time stability data — 36 months @ −20 °C

ICH Q1A(R2) · long-term + accelerated arms

t (mo)	Storage	Assay (HPLC)	Δ vs t₀	Endotoxin	Water (KF)	Status
0	−20 °C, dry	99.74%	reference	< 0.05 EU/mg	2.3%	● t₀
3	−20 °C, dry	99.73%	−0.01%	< 0.05 EU/mg	2.3%	● within spec
6	−20 °C, dry	99.71%	−0.03%	< 0.05 EU/mg	2.4%	● within spec
12	−20 °C, dry	99.65%	−0.09%	< 0.05 EU/mg	2.5%	● within spec
24	−20 °C, dry	99.52%	−0.22%	< 0.05 EU/mg	2.6%	● within spec
36	−20 °C, dry	99.41%	−0.33%	< 0.07 EU/mg	2.7%	● within spec

Test points t = 0, 3, 6, 9, 12, 18, 24, 30, 36 mo. Acceptance criterion: assay ≥ 95.0% of t₀, endotoxin < 5.0 EU/mg, water ≤ 5.0% w/w. Accelerated arm 25 °C / 60% RH passed without specification deviation through 6 months.

Analytical method strings

validated per ICH Q2(R1) · linearity / accuracy / precision / specificity / LOD-LOQ

RP-HPLC · purity / assay

Phenomenex Luna C18(2), 250 × 4.6 mm, 5 μm. Mobile A: 0.1% TFA in H₂O · B: 0.1% TFA in MeCN. Gradient 20 → 80% B over 30 min, hold 5 min. Flow 1.0 mL/min. Column 35 °C. UV-DAD 220 nm. Injection 20 μL · 1 mg/mL.

ESI-Q-TOF MS · identity

Bruker Compact Q-TOF · positive ion. m/z 100 – 6000. Capillary 4500 V. Nebuliser 1.6 bar. Dry gas 8.0 L/min @ 200 °C. Mass accuracy ±0.5 Da of theoretical [M+H]⁺ / [M+2H]²⁺ / [M+3H]³⁺.

LAL kinetic chromogenic · endotoxin

Charles River Endosafe nexgen-PTS · USP <85> / EP 2.6.14 / JP 4.01. Sensitivity 0.005 – 50 EU/mL. MVD calculated from CSE. Acceptance: spike recovery 50 – 200%; r ≥ 0.980 over standard curve.

Karl-Fischer · water content

Metrohm 870 KF Titrino plus · coulometric. Anode HYDRANAL Coulomat AG. Sample 50 – 100 mg, headspace-free. Acceptance ≤ 5.0% w/w. Reported to 0.1% precision. Cross-checked vs. TGA.

ICP-MS · elemental impurities

Agilent 7900 ICP-MS · ICH Q3D Option 1. Sample digestion: closed-vessel microwave (HNO₃ + H₂O₂). Target panel: Pb, Cd, As, Hg + Class 2A/2B. RSD ≤ 5%. Recovery 70 – 150% of spiked control.

AAA · amino-acid analysis

Hitachi L-8900 · post-column ninhydrin. Hydrolysis 6 N HCl · 110 °C · 24 h, vacuum-sealed, phenol added. Reports residue ratios + net peptide content (anchor for assay value). Cross-validated vs. nitrogen elemental analysis.

Quality system

ISO 9001:2015 certified

Certificate CN-11/Q-2417 · TÜV Rheinland

Test laboratory

ISO/IEC 17025 accredited

Scope: chemical & biological testing

Manufacturing

ICH Q7-aligned API

Process validation 3 consecutive batches

Compendial cross-ref

USP-NF · EP · JP · ChP

Specifications mapped to monograph chapters

Place an order against this catalog

Bulk pricing, milligram–gram scale, full CoA on every shipment

Order online →

Pharma-grade research peptides & analytical reference compounds from a multi-warehouse network.

Live inventory · catalog

QC specifications · catalog-wide

Reference standard — full analytical profile

Endotoxin · microbial limits · elemental impurities

Residual solvents — ICH Q3C(R8)

Real-time stability data — 36 months @ −20 °C

Analytical method strings

Order online · technical support

Place an order on the catalog

// Technical support